{"id":559,"date":"2025-10-10T11:43:11","date_gmt":"2025-10-10T02:43:11","guid":{"rendered":"https:\/\/gpu-advchem.jp\/?p=559"},"modified":"2025-10-10T12:03:38","modified_gmt":"2025-10-10T03:03:38","slug":"%e3%83%95%e3%83%ad%e3%83%bc%e5%bc%8f-mizoroki-heck-%e5%8f%8d%e5%bf%9c%e3%81%a7-14-%e6%97%a5%e9%80%a3%e7%b6%9a%e3%81%ae%e9%ab%98%e5%a4%89%e6%8f%9b%e3%82%92%e5%ae%9f%e8%a8%bc-%e2%80%95-pnp","status":"publish","type":"post","link":"https:\/\/gpu-advchem.jp\/?p=559","title":{"rendered":"\u30d5\u30ed\u30fc\u5f0f Mizoroki\u2013Heck \u53cd\u5fdc\u3067 14 \u65e5\u9023\u7d9a\u306e\u9ad8\u5909\u63db\u3092\u5b9f\u8a3c \u2015 PNP\u30ea\u30ac\u30f3\u30c9\u3068\u5869\u57fa\u6700\u9069\u5316\u3067Pd\u89e6\u5a92\u6d3b\u6027\u306e\u7dad\u6301\u306b\u6210\u529f \u2015"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-569 size-full\" src=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025.jpg\" alt=\"\" width=\"600\" height=\"338\" srcset=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025.jpg 600w, https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025-300x169.jpg 300w, https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025-320x180.jpg 320w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>\u6982\u8981<\/strong><\/p>\n<p>PNP \u30d4\u30f3\u30b5\u30fc\u914d\u4f4d\u5b50\u3067\u8a2d\u8a08\u3057\u305f\u6a39\u8102\u56fa\u5b9a\u5316\u30d1\u30e9\u30b8\u30a6\u30e0\u89e6\u5a92 <strong>Pd-SCORPI<\/strong> \u3092\u958b\u767a\u3057\u3001\u9023\u7d9a\u30d5\u30ed\u30fcMizoroki\u2013Heck\u53cd\u5fdc\u306b\u304a\u3044\u3066<strong>14\u65e5\u9593<\/strong>\u306b\u308f\u305f\u308a<strong>&gt;92%<\/strong>\u306e\u9ad8\u5909\u63db\u3092\u7dad\u6301\uff08<strong>TON 1115, TOF 3.32 h<\/strong><strong>\u207b<\/strong><strong>\u00b9<\/strong>\uff09\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u305f\u3002\u89e6\u5a92\u306f\u904b\u8ee2\u521d\u671f\u306b<strong>\u5358\u539f\u5b50\u72b6\uff08\u9ad8\u5206\u6563\uff09<\/strong>\u3067\u652f\u6301\u3055\u308c\u3001\u53cd\u5fdc\u9032\u884c\u3068\u3068\u3082\u306b <strong>Pd\u30ca\u30ce\u7c92\u5b50<\/strong>\u3078\u3068\u6210\u9577\u3059\u308b\u304c\u3001<strong>PNP\u30ea\u30ac\u30f3\u30c9\u8a2d\u8a08\u3068\u5869\u57fa\u6761\u4ef6\u306e\u6700\u9069\u5316<\/strong>\u306b\u3088\u308a<strong>Pd\u30ea\u30fc\u30c1\u30f3\u30b0\u3092\u6700\u5c0f\u9650<\/strong>\u306b\u6291\u3048\u3001\u9577\u6642\u9593\u306e\u9ad8\u6d3b\u6027\u30fb\u9ad8\u9078\u629e\u3092\u4e21\u7acb\u3057\u305f\u3002\u3055\u3089\u306b\u3001Suzuki\u2013Miyaura\u53cd\u5fdc\u3067\u3082<strong>\u5ba4\u6e29\u30fb150 \u6642\u9593<\/strong>\u306e\u5b89\u5b9a\u7a3c\u50cd\uff08\u53ce\u7387 91%\u3001TON 1242\uff09\u3092\u78ba\u8a8d\u3057\u3001\u30b0\u30ea\u30fc\u30f3\u304b\u3064\u30b9\u30b1\u30fc\u30e9\u30d6\u30eb\u306aC\u2013C\u7d50\u5408\u5f62\u6210\u30d7\u30ed\u30bb\u30b9\u3068\u3057\u3066\u306e\u5b9f\u88c5\u6027\u3092\u793a\u3057\u305f\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-560 size-full\" src=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025-1.png\" alt=\"\" width=\"514\" height=\"469\" srcset=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025-1.png 514w, https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025-1-300x274.png 300w\" sizes=\"auto, (max-width: 514px) 100vw, 514px\" \/><\/p>\n<p><strong>\u7814\u7a76\u306e\u80cc\u666f<\/strong><\/p>\n<p>Pd\u89e6\u5a92\u306b\u3088\u308bC\u2013C\u7d50\u5408\u5f62\u6210\u306f\u533b\u85ac\u30fb\u6a5f\u80fd\u6027\u6750\u6599\u5408\u6210\u306e\u8981\u3067\u3042\u308b\u304c\u3001<strong>\u91d1\u5c5e\u30ea\u30fc\u30c1\u30f3\u30b0<\/strong>\u304c\u9023\u7d9a\u904b\u8ee2\u30fb\u54c1\u8cea\u4fdd\u8a3c\u306e\u30dc\u30c8\u30eb\u30cd\u30c3\u30af\u3067\u3042\u3063\u305f\u3002\u672c\u7814\u7a76\u3067\u306f\u3001<strong>\u525b\u76f4\u306a\u4e09\u5ea7\u914d\u4f4d\u306ePNP\u30d4\u30f3\u30b5\u30fc<\/strong>\u306b\u3088\u3063\u3066\u914d\u4f4d\u4e0d\u98fd\u548c\u7a2e\u306e\u4e0d\u5b89\u5b9a\u5316\u3092\u6291\u3048\u3001<strong>Merrifield\u6a39\u8102\u3078\u306e\u56fa\u5b9a\u5316<\/strong>\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001<strong>\u5747\u4e00\u7cfb\u89e6\u5a92\u306e\u5f37\u6d3b\u6027<\/strong>\u3068<strong>\u4e0d\u5747\u4e00\u7cfb\u89e6\u5a92\u306e\u56de\u53ce\u5bb9\u6613\u6027<\/strong>\u3092\u4e21\u7acb\u3002\u9023\u7d9a\u30d5\u30ed\u30fc\u74b0\u5883\u306b\u304a\u3051\u308b<strong>\u9577\u6642\u9593\u5b89\u5b9a\u6027<\/strong>\u3068<strong>\u91d1\u5c5e\u7ba1\u7406<\/strong>\u306e\u8ab2\u984c\u89e3\u6c7a\u3092\u76ee\u6307\u3057\u305f\u3002<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>\u7814\u7a76\u306e\u30dd\u30a4\u30f3\u30c8<\/strong><\/p>\n<p>\u30fb<strong>Pd\u30ea\u30fc\u30c1\u30f3\u30b0\u306e\u5236\u5fa1<br \/>\n<\/strong>\u521d\u671f\u306f<strong>\u5358\u539f\u5b50\u72b6\u306b\u8fd1\u3044\u9ad8\u5206\u6563Pd<\/strong>\u304c\u6d3b\u6027\u70b9\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001\u904b\u8ee2\u306e\u9032\u884c\u306b\u4f34\u3044<strong>Pd\u30ca\u30ce\u7c92\u5b50<\/strong>\u304c\u5f62\u6210\u30fb\u6210\u9577\u3002<strong>PNP\u30ea\u30ac\u30f3\u30c9\u8a2d\u8a08\u3068\u5869\u57fa\u9078\u629e<\/strong> \u306b\u3088\u308a\u3001\u3053\u306e\u9032\u5316\u904e\u7a0b\u3067\u306e<strong>\u30ea\u30fc\u30c1\u30f3\u30b0\u3092\u6700\u5c0f\u5316<\/strong>\u3001\u6d3b\u6027\u3068\u8010\u4e45\u6027\u3092\u4e21\u7acb\u3002<\/p>\n<p>\u203b\u6700\u9069\u6761\u4ef6\u4e0b\u3067\u306e\u53cd\u5fdc\u5f8c\u6db2\u4e2dPd\u306f<strong>\u4f4e\u6fc3\u5ea6\uff08ICP-AES \u5b9a\u91cf\u30011\u20138 ppm\/\u6642\u753b\u5206\uff09<\/strong>\u3002<\/p>\n<p>\u30fb<strong>Heck\u53cd\u5fdc\u3067\u306e\u9577\u671f\u9023\u7d9a\u904b\u8ee2<\/strong><br \/>\n4-iodoanisole\uff0bn-butyl acrylate\uff08DMF, 120 \u00b0C, 0.05 mL min\u207b\u00b9\uff09\u3067 <strong>&gt;92% \u5909\u63db\u3092 14 \u65e5\u7dad\u6301<\/strong>\u3001<strong>TON 1115 \/ TOF 3.32 h<\/strong><strong>\u207b<\/strong><strong>\u00b9<\/strong>\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-561 size-full\" src=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/\u753b\u50cf2-\u4fee\u6b63.jpg\" alt=\"\" width=\"503\" height=\"385\" srcset=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/\u753b\u50cf2-\u4fee\u6b63.jpg 503w, https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/\u753b\u50cf2-\u4fee\u6b63-300x230.jpg 300w\" sizes=\"auto, (max-width: 503px) 100vw, 503px\" \/><\/p>\n<p>\u30fb<strong>\u57fa\u8cea\u9069\u7528\u7bc4\u56f2\u306e\u5e83\u3055<\/strong><br \/>\n<strong>EDG\/EWG<\/strong> \u3092\u554f\u308f\u305a\u5e83\u7bc4\u306a\u30a2\u30ea\u30fc\u30eb\u30cf\u30e9\u30a4\u30c9\u00d7\u7a2e\u3005\u306e\u30a2\u30eb\u30b1\u30f3\u306b\u9069\u7528\u3002<strong>\u30a2\u30af\u30ea\u30eb\u9178\u30fb\u30a2\u30af\u30ea\u30eb\u30a2\u30df\u30c9<\/strong> \u306a\u3069\u306e\u57fa\u8cea\u306b\u3082\u5bfe\u5fdc\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-562 size-full\" src=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025-3.png\" alt=\"\" width=\"354\" height=\"436\" srcset=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025-3.png 354w, https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/ChemSusChem2025-3-244x300.png 244w\" sizes=\"auto, (max-width: 354px) 100vw, 354px\" \/><\/p>\n<p>\u30fb<strong>Suzuki\u53cd\u5fdc\u306e\u6e29\u548c\u6761\u4ef6\u5b9f\u8a3c<\/strong><br \/>\n4-iodoacetophenone\uff0b\u30d5\u30a7\u30cb\u30eb\u30dc\u30ed\u30f3\u9178\uff08<strong>H\u2082O\/1,4-\u30b8\u30aa\u30ad\u30b5\u30f3 = 1:3, \u5ba4\u6e29, 0.05 mL min<\/strong><strong>\u207b<\/strong><strong>\u00b9<\/strong>\uff09\u3067 <strong>\u53ce\u7387 91%<\/strong>\u3001<strong>TON 1242<\/strong>\u3001<strong>150 h<\/strong> \u5b89\u5b9a\u904b\u8ee2\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-563 size-full\" src=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/\u753b\u50cf4\u4fee\u6b63.jpg\" alt=\"\" width=\"479\" height=\"352\" srcset=\"https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/\u753b\u50cf4\u4fee\u6b63.jpg 479w, https:\/\/gpu-advchem.jp\/wp-content\/uploads\/2025\/10\/\u753b\u50cf4\u4fee\u6b63-300x220.jpg 300w\" sizes=\"auto, (max-width: 479px) 100vw, 479px\" \/><\/p>\n<p><strong>\u6210\u679c\u306e\u610f\u7fa9<\/strong><\/p>\n<p>\u30fb<strong>\u6301\u7d9a\u53ef\u80fd\u306a\u30d7\u30ed\u30bb\u30b9\u8a2d\u8a08<\/strong>\uff1a\u56fa\u5b9a\u5316 Pd \u306b\u3088\u308a<strong>\u56de\u53ce\u30fb\u518d\u4f7f\u7528<\/strong>\u304c\u5bb9\u6613\u3001<strong>\u5ec3\u68c4\u7269\u3068\u6eb6\u5a92\u4f7f\u7528\u3092\u524a\u6e1b<\/strong>\u3002<\/p>\n<p>\u30fb<strong>\u30b9\u30b1\u30fc\u30eb\u30a2\u30a6\u30c8\u9069\u6027<\/strong>\uff1a<strong>kg\u30b9\u30b1\u30fc\u30eb<\/strong>\u306e\u9023\u7d9a\u88fd\u9020\u3078\u76f4\u7d50\u3001<strong>\u54c1\u8cea\u4e00\u8cab\u6027<\/strong>\u3068<strong>\u5b89\u5168\u6027<\/strong>\u3092\u4e21\u7acb\u3002<\/p>\n<p>\u30fb<strong>\u6a5f\u69cb\u8a2d\u8a08\u6307\u91dd\u306e\u63d0\u4f9b<\/strong>\uff1a<strong>\u5358\u539f\u5b50\u72b6\u2192\u30ca\u30ce\u7c92\u5b50<\/strong>\u306e<strong>in situ\u6210\u9577<\/strong>\u3092\u524d\u63d0\u306b\u3001<strong>\u30ea\u30ac\u30f3\u30c9\u30fb\u5869\u57fa\u3067\u30ea\u30fc\u30c1\u30f3\u30b0\u3092\u6291\u5236<\/strong>\u3059\u308b\u8a2d\u8a08\u3092\u63d0\u793a\u3002Heck \u4ee5\u5916\u306e\u30af\u30ed\u30b9\u30ab\u30c3\u30d7\u30ea\u30f3\u30b0\/\u6c34\u7d20\u5316\u30fb\u8131\u6c34\u7d20\u5316\u306b\u3082\u6ce2\u53ca\u53ef\u80fd\u3002<\/p>\n<p>\u30fb<strong>\u30b0\u30ea\u30fc\u30f3\u30b1\u30df\u30b9\u30c8\u30ea\u30fc\u306e\u5b9f\u88c5<\/strong>\uff1a<strong>\u30a8\u30cd\u30eb\u30ae\u30fc\u30fb\u8cc7\u6e90\u52b9\u7387<\/strong>\u3068<strong>\u91d1\u5c5e\u7ba1\u7406<\/strong>\u3092\u4e21\u7acb\u3057\u3001<strong>GMP\/\u54c1\u8cea\u4fdd\u8a3c<\/strong>\u3092\u898b\u636e\u3048\u305f\u9023\u7d9a\u751f\u7523\u6280\u8853\u306e\u57fa\u76e4\u3092\u63d0\u4f9b\u3002<\/p>\n<p><strong>\u8ad6\u6587\u60c5\u5831<\/strong><\/p>\n<ul>\n<li><strong>\u96d1\u8a8c\u540d<\/strong>: <em>ChemSusChem<\/em><\/li>\n<li><strong>\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb<\/strong>: <em>Durable Heterogeneous Pd-PNP Pincer Complex for Carbon\u2013Carbon Bond Formation in<\/em><em> Continuous-Flow Systems<\/em><\/li>\n<li><strong>\u8457\u8005<\/strong>: Naoya\u00a0Sakurada, Kanon Kawai, Yuka Abe, Kwihwan Kobayashi, Shinya Mine, Noriko Miyamoto, Tsuyoshi Yamada, Takashi Ikawa, Hironao Sajiki<\/li>\n<li><strong>DOI<\/strong>: <a href=\"https:\/\/doi.org\/10.1002\/cssc.202501205\" target=\"_blank\" rel=\"noopener\">10.1002\/cssc.202501205<\/a><\/li>\n<li><strong>\u63b2\u8f09\u65e5<\/strong>: 2025\u00a0\u5e74\u00a08\u00a0\u6708\u00a030\u00a0\u65e5\u30aa\u30f3\u30e9\u30a4\u30f3\u516c\u958b<\/li>\n<\/ul>\n<p><strong>\u7528\u8a9e\u89e3\u8aac<\/strong><\/p>\n<p><strong>\u30fbPNP\u30d4\u30f3\u30b5\u30fc\u914d\u4f4d\u5b50\uff08PNP pincer ligand\uff09<\/strong><br \/>\n\u4e09\u5ea7\uff08P\u2013N\u2013P\uff09\u306e\u786c\u76f4\u7684\u306a\u4e09\u70b9\u914d\u4f4d\u3067\u91d1\u5c5e\u4e2d\u5fc3\u3092\u5f37\u56fa\u306b\u4fdd\u6301\u3059\u308b\u914d\u4f4d\u5b50\u3002\u96fb\u5b50\u30fb\u7acb\u4f53\u74b0\u5883\u3092\u7cbe\u5bc6\u306b\u8abf\u6574\u3067\u304d\u3001\u89e6\u5a92\u306e\u5b89\u5b9a\u5316\u3068\u9078\u629e\u6027\u5411\u4e0a\u306b\u5bc4\u4e0e\u3059\u308b\u3002<\/p>\n<p><strong>\u30fb\u5358\u539f\u5b50\u89e6\u5a92\uff08Single-atom catalyst\uff09<\/strong><br \/>\n\u62c5\u4f53\u8868\u9762\u306b\u201c\u5b64\u7acb\u539f\u5b50\u201d\u30ec\u30d9\u30eb\u3067\u5206\u6563\u3057\u305f\u91d1\u5c5e\u6d3b\u6027\u70b9\u3002\u91d1\u5c5e\u5229\u7528\u52b9\u7387\u304c\u9ad8\u304f\u3001\u9078\u629e\u6027\u306b\u512a\u308c\u308b\u4e00\u65b9\u3001\u6761\u4ef6\u306b\u3088\u3063\u3066\u306f\u51dd\u96c6\u3057\u3084\u3059\u3044\u3002<\/p>\n<p><strong>\u30fb\u30ca\u30ce\u7c92\u5b50\u5316\uff08Nanoparticle formation\uff09<\/strong><br \/>\n\u5358\u539f\u5b50\u3084\u6570\u539f\u5b50\u30af\u30e9\u30b9\u30bf\u30fc\u304c\u6210\u9577\u30fb\u51dd\u96c6\u3057\u3066 1\u2013100 nm \u7a0b\u5ea6\u306e\u7c92\u5b50\u306b\u306a\u308b\u73fe\u8c61\u3002\u6d3b\u6027\u30fb\u9078\u629e\u6027\u30fb\u6eb6\u51fa\u6319\u52d5\u304c\u5909\u5316\u3057\u3046\u308b\u3002<\/p>\n<p><strong>\u30fb\u30ea\u30fc\u30c1\u30f3\u30b0\uff08Leaching\uff0f\u6eb6\u51fa\uff09<\/strong><br \/>\n\u89e6\u5a92\u4e2d\u306e\u91d1\u5c5e\u304c\u6eb6\u6db2\u5074\uff0f\u6d41\u51fa\u6db2\u3078\u79fb\u884c\u3059\u308b\u73fe\u8c61\u3002\u6d3b\u6027\u4f4e\u4e0b\u3084\u88fd\u54c1\u306e\u91d1\u5c5e\u4e0d\u7d14\u7269\u30ea\u30b9\u30af\u306b\u3064\u306a\u304c\u308b\u305f\u3081\u3001\u9023\u7d9a\u751f\u7523\u3067\u306f\u6700\u91cd\u8981\u7ba1\u7406\u9805\u76ee\u3002<\/p>\n<p><strong>\u30fbTON\uff0fTOF<\/strong><\/p>\n<p><strong>TON\uff08Turnover Number\uff09<\/strong>\uff1a\u89e6\u5a92 1 \u30e2\u30eb\u3042\u305f\u308a\u304c\u751f\u6210\u3059\u308b\u751f\u6210\u7269\u306e\u7dcf\u30e2\u30eb\u6570\uff08\u7d2f\u7a4d\u56de\u8ee2\u6570\uff09\u3002\u200b<\/p>\n<p><strong>TOF\uff08Turnover Frequency\uff09<\/strong>\uff1a\u5358\u4f4d\u6642\u9593\u3042\u305f\u308a\u306e\u56de\u8ee2\u6570\u3002\u901a\u5e38 h\u207b\u00b9 \u3092\u7528\u3044\u308b\u3002<\/p>\n<p><strong>\u30d5\u30ed\u30fc\u5408\u6210\uff08Continuous-flow synthesis\uff0f\u9023\u7d9a\u30d5\u30ed\u30fc\uff09<\/strong><br \/>\n\u539f\u6599\u6eb6\u6db2\u3084\u30ac\u30b9\u3092\u9023\u7d9a\u7684\u306b\u53cd\u5fdc\u5668\u3078\u9001\u6db2\u3057\u3001\u751f\u6210\u7269\u3092\u9023\u7d9a\u56de\u53ce\u3059\u308b\u65b9\u5f0f\u3002\u71b1\u30fb\u7269\u8cea\u79fb\u52d5\u304c\u826f\u597d\u3067\u3001\u5b89\u5168\u6027\u30fb\u518d\u73fe\u6027\u30fb\u30b9\u30b1\u30fc\u30eb\u30a2\u30a6\u30c8\u6027\u306b\u512a\u308c\u308b\u3002<\/p>\n<p><strong>\u30fbMizoroki\u2013Heck \u53cd\u5fdc\uff08\u30d8\u30c3\u30af\u53cd\u5fdc\uff09<\/strong><br \/>\n\u30a2\u30ea\u30fc\u30eb\u30cf\u30e9\u30a4\u30c9\u3068\u30a2\u30eb\u30b1\u30f3\u306ePd\u89e6\u5a92\u30af\u30ed\u30b9\u30ab\u30c3\u30d7\u30ea\u30f3\u30b0\u3002C\u2013C\u7d50\u5408\u5f62\u6210\u306e\u57fa\u76e4\u53cd\u5fdc\u306e\u4e00\u3064\u3002<\/p>\n<p><strong>\u30fbSuzuki\u2013Miyaura \u53cd\u5fdc\uff08\u9234\u6728\u2013\u5bae\u6d66\u53cd\u5fdc\uff09<\/strong><br \/>\n\u30a2\u30ea\u30fc\u30eb\u30cf\u30e9\u30a4\u30c9\u3068\u6709\u6a5f\u30dc\u30ed\u30f3\u5316\u5408\u7269\u306ePd\u89e6\u5a92\u30af\u30ed\u30b9\u30ab\u30c3\u30d7\u30ea\u30f3\u30b0\u3002\u6e29\u548c\u30fb\u5b98\u80fd\u57fa\u8a31\u5bb9\u6027\u304c\u9ad8\u3044\u3002<\/p>\n<p><strong>\u30fb\u56fa\u5b9a\u5316\u89e6\u5a92\uff08Immobilized\/heterogeneous catalyst\uff09<\/strong><br \/>\n\u89e6\u5a92\u6210\u5206\u3092\u56fa\u4f53\u62c5\u4f53\u306b\u56fa\u5b9a\u3057\u305f\u7cfb\u3002\u56de\u53ce\u30fb\u518d\u4f7f\u7528\u3084\u6b8b\u7559\u91d1\u5c5e\u7ba1\u7406\u304c\u5bb9\u6613\u3002<br \/>\n\u672c\u7814\u7a76\u3067\u306f<strong>Merrifield\u6a39\u8102<\/strong>\u306bPNP\u30ea\u30ac\u30f3\u30c9\u3092\u5171\u6709\u7d50\u5408\u7684\u306b\u56fa\u5b9a\u5316\u3057\u3001\u30d5\u30ed\u30fc\u904b\u8ee2\u4e0b\u3067\u306e\u8010\u4e45\u6027\u3092\u78ba\u4fdd\u3002<\/p>\n<p><strong>\u00a0<\/strong><strong>\u30fbMerrifield\u6a39\u8102\uff08Merrifield resin\uff09<\/strong><br \/>\n\u5869\u5316\u30d9\u30f3\u30b8\u30eb\u57fa\u3092\u6709\u3059\u308b\u67b6\u6a4b\u30dd\u30ea\u30b9\u30c1\u30ec\u30f3\u6a39\u8102\u3002\u7f6e\u63db\u53cd\u5fdc\u3067\u914d\u4f4d\u5b50\uff0f\u91d1\u5c5e\u3092\u5c0e\u5165\u3057\u3084\u3059\u304f\u3001\u56fa\u76f8\u5408\u6210\u3084\u56fa\u5b9a\u5316\u89e6\u5a92\u306e\u62c5\u4f53\u3068\u3057\u3066\u5e83\u304f\u7528\u3044\u3089\u308c\u308b\u3002<\/p>\n<p><strong>\u7814\u7a76\u5ba4\u60c5\u5831\u30fb\u304a\u554f\u3044\u5408\u308f\u305b<\/strong><\/p>\n<ul>\n<li><strong>\u5c90\u961c\u85ac\u79d1\u5927\u5b66\u3000\u30a2\u30c9\u30d0\u30f3\u30b9\u30c8\u30b1\u30df\u30b9\u30c8\u30ea\u30fc\u7814\u7a76\u5ba4<\/strong><br \/>\n\u3012501\u20111196 \u5c90\u961c\u5e02\u5927\u5b66\u897f 1\u201125\u20114<br \/>\nTEL\u00a0058\u2011230\u20118100\uff08\u5185\u7dda\u00a03621\uff09<br \/>\nWeb: https:\/\/gpu-advchem.jp<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u6982\u8981 PNP \u30d4\u30f3\u30b5\u30fc\u914d\u4f4d\u5b50\u3067\u8a2d\u8a08\u3057\u305f\u6a39\u8102\u56fa\u5b9a\u5316\u30d1\u30e9\u30b8\u30a6\u30e0\u89e6\u5a92 Pd-SCORPI \u3092\u958b\u767a\u3057\u3001\u9023\u7d9a\u30d5\u30ed\u30fcMizoroki\u2013Heck\u53cd\u5fdc\u306b\u304a\u3044\u306614\u65e5\u9593\u306b\u308f\u305f\u308a&gt;92%\u306e\u9ad8\u5909\u63db\u3092\u7dad\u6301\uff08TON 1115, TOF 3. [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":569,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"sns_share_botton_hide":"","vkExUnit_sns_title":"","_vk_print_noindex":"","sitemap_hide":"","_veu_custom_css":"","veu_display_promotion_alert":"common","vkexunit_cta_each_option":"","footnotes":""},"categories":[10],"tags":[],"class_list":["post-559","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-10"],"veu_head_title_object":{"title":"","add_site_title":""},"_links":{"self":[{"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=\/wp\/v2\/posts\/559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=559"}],"version-history":[{"count":5,"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=\/wp\/v2\/posts\/559\/revisions"}],"predecessor-version":[{"id":571,"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=\/wp\/v2\/posts\/559\/revisions\/571"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=\/wp\/v2\/media\/569"}],"wp:attachment":[{"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=559"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=559"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gpu-advchem.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}